GRADUATE PROGRAM IN COMPARATIVE AND EXPERIMENTAL MEDICINE
GRADUATE PROGRAM
IN
COMPARATIVE AND EXPERIMENTAL MEDICINE
MAJOR: Comparative and Experimental
Medicine (CEM)
DEGREES: M.S., Ph.D.
POLICY AND PROCEDURES
Administered by
THE JOINT GRADUATE COORDINATING COMMITTEE
Robert N. Moore, Ph.D., Director
M.D. Karlstad, Ph.D.
J. E. Lawler, Ph.D.
C. Lozzio, M.D.
The University of Tennessee
COLLEGE OF VETERINARY MEDICINE
Michael Blackwell, Dean
The University of Tennessee
GRADUATE SCHOOL OF MEDICINE
Michael R. Caudle, Dean
The Comparative and Experimental Medicine (CEM) degree program (M.S. and Ph.D.) is a jointly administered graduate program intended to prepare students for teaching and/or research careers in the health sciences. This program emphasizes the comparative approach to the study of experimental patho-biology, infectious disease, pharmacokinetics, epidemiology, clinical medicine, immuno-pathology, hematology, aberrant metabolism, oncology, and genetic disorders. The Ph.D. program is open to approved graduate students seeking training in this area and is especially useful for individuals with professional degrees. For the student with an undergraduate biological science background, the CEM program provides an unusual opportunity to study disease processes common in humans and animals from a multi-disciplinary perspective. The scope of this intercollegiate program, which pools faculty resources from both veterinary and human medicine, is broadened by faculty members representing animal science and numerous areas of the life sciences. The interdisciplinary training environment includes such diverse support as facilities and personnel at the UT Veterinary Teaching Hospital, UT Medical Center at Knoxville, the Oak Ridge National Laboratory, Knoxville Zoological Park, Hemophilia Clinic, Developmental and Genetic Center, Hematology and Oncology Services, and Department of Life Sciences.
APPLICATION
For additional program information, contact Debbie Hampstead at dhampste@utk.edu or print an application from this web site.
ADMISSION REQUIREMENTS
GENERAL
Admission requirements of The University of Tennessee-Knoxville Graduate School apply to prospective students of the CEM program. In addition, applicants must furnish three letters of recommendation from individuals familiar with their scholastic or professional records.
REQUIREMENTS FOR ADMISSION TO THE MASTER OF SCIENCE DEGREE PROGRAM
Applicants to the M.S. degree program must have a baccalaureate degree with course work in chemistry through organic, mathematics through calculus, physics, and basic biology. More advanced study in biology, such as biochemistry, mammalian anatomy, histology, cell biology, or other appropriate biomedical courses from a recognized university is recommended.
Applicants for admission to the master's degree program whose backgrounds include no formal training in the biomedical field beyond the baccalaureate degree must score at least 1,000 on the quantitative and verbal portion of the Graduate Record Examination.
REQUIREMENTS FOR ADMISSION TO THE DOCTOR OF PHILOSOPHY DEGREE PROGRAM
Applicants generally will be expected to have a professional degree in one of the medical sciences (e.g., M.D., D.D.S., D.V.M.) or a master's degree in one of the biomedical sciences and a Graduate Record Examination score of at least 1,000 for the quantitative and verbal sections.
An individual having a baccalaureate degree with a strong background in the physical and biological sciences may be admitted upon presenting evidence of exemplary performance on the Graduate Record Examination.
Exceptional veterinary students at The University of Tennessee, Knoxville may be
admitted to the CEM program but will remain enrolled officially as veterinary students.
Such students may register for graduate courses, and they may be counted as elective
courses in the veterinary program.
DEGREE REQUIREMENTS
MASTER OF SCIENCE
Minimum Coursework :
Core 10 hours
Required (Major) 9 hours
Thesis 6 hours
Electives 5 hours
Total 30 hours
Core courses are required for the program. A basic science and/or applied science concentration must be selected at the first meeting of the student's master's committee. For the basic science concentration, students must take at least 4 credit hours in 500- or 600- level courses in basic mechanisms of disease and at least 6 credit hours of 500- level biochemistry or cell biology. See listings under the Biochemistry and Cellular and Molecular Biology program for information on these courses. For the applied science concentration, students must take at least 6 credit hours of 600- level epidemiology and at least 5 credit hours of 500- or 600- level statistics. In addition, students must complete a minimum of 8 hours of coursework in a specified discipline, 5 or more hours of electives, and 6 hours of Thesis 500. Exceptions to accommodate students with specific interests must be approved by the Joint Graduate Coordinating Committee after application, in writing, to the director.
A minimum of half the total hours of coursework required for a master's degree must be taken at The University of Tennessee-Knoxville. A maximum of one-third of the total hours may be transferred from institutions outside The University of Tennessee system with approval by the student's Master's Committee and The Graduate School. Graduate courses (500- or 600-level) taken by veterinary, medical, and dental students may, if appropriate, be transferred or credited (maximum of 6 hours) to a student's graduate program in Comparative and Experimental Medicine upon recommendation by the student's Master's Committee and approval by a majority of the Joint Graduate Coordinating Committee (see transfer credits page 8).
MASTER'S COMMITTEE
Students must consult with the program director on selection of an advisor (or temporary advisor) upon entry into the graduate program. After one semester of graduate-level courses, the student should select and consult with the advisor concerning the formation of a Master's Committee (at least three members). The committee must be composed of at least one faculty member from the College of Veterinary Medicine and at least one faculty member from the UT Graduate School of Medicine. The director, after consulting with the Joint Graduate Coordinating Committee, must approve the Master's Committee to ensure balance and that the CEM program is appropriately represented. If the student opts for a significant amount of coursework in a minor field of study, one member of the committee must be from an appropriate department in the minor discipline. The committee will assist the student in planning a course of study prior to the end of the second semester of graduate-level work. The committee may require and/or recommend specific courses (in addition to those required by the program). The committee should aid the student in formulating and completing an appropriate research project, and ensuring the achievement of degree requirements. The student is responsible for coordinating meetings of the Master's Committee and obtaining and/or preparing required materials such as appropriate Graduate School forms, transcripts, progress reports and research proposals for the meetings. Student progress will be monitored by the program director. It is incumbent upon students to honor promptly requests for progress reports.
ADMISSION TO CANDIDACY
Application for admission to candidacy for the master's degree may be made after the student has completed required prerequisite courses and 9 hours of graduate coursework and has a minimum GPA of 3.0. Students must submit the Admission to Candidacy form, with appropriate signatures, to the Office of Graduate Admissions and Records no later than commencement day of the semester preceding the semester in which they plan to graduate.
THESIS REGISTRATION
Students must be registered for thesis hours each semester work is done on the thesis (continuous registration is not required), including a minimum of three hours the semester in which the thesis is accepted by The Graduate School. Six hours of course number 500 are required. After receiving the Master's degree, a student is no longer permitted to register for 500-level thesis hours.
FINAL EXAMINATION
Candidates presenting a thesis MUST pass a final oral (or oral and written) examination, as determined by the candidate's committee. The examination, which is concerned with both coursework and the thesis, measures the candidate's ability to integrate material in the major and related fields. The final draft of the thesis must be distributed to all committee members at least two weeks prior to the date of the final examination. Unless prior approval from The Graduate School is granted, the examination must be given in University facilities. This examination must be scheduled by the student through the Office of Graduate Admissions and Records, at least one week prior to the examination. Final examinations not properly scheduled MUST be repeated. This examination must be held at least two weeks before the final date for acceptance and approval of thesis set by The Graduate School. Results of the final examination must be submitted by the thesis deadline. In case of failure, the candidate may not apply for re-examination until the following semester. The result of the second examination is final.
THESIS
The thesis is the culmination of an original research project completed by the student. The final draft of the thesis must be distributed to all committee members at least two weeks prior to the date of the final oral examination. A draft of the thesis should be placed in the CEM Office of Graduate Programs at least one week prior to the final examination and available to all interested persons at The University of Tennessee. It must be prepared according to the current edition of the UTK Guide for the Preparation of Theses and Dissertations. Thesis preparation is the responsibility of the student (this includes typing and photocopying). Two copies of the thesis must be approved and accepted by The Graduate School on or before the deadline specified each semester in the Graduate School News. Each copy must include an approval sheet, signed by the members of the Master's Committee, certifying that they have examined the final copy of the thesis and judged it to be satisfactory.
TRANSFER CREDITS
Courses taken at another institution may be considered for transfer into the M.S. degree program, as determined by the Master's Committee and approved by The Graduate School. Official transcripts must be sent directly to the Office of Graduate Admissions and Records from all institutions previously attended before any credit will be considered. Courses transferred to the graduate program will not affect the minimum residence requirements for the program, nor will they be counted in determining the student's grade-point average. Credits transferred from universities outside The University of Tennessee system cannot be used to meet the 500- or 600-level course work requirements. Credit for extension courses taken from other institutions is not transferable, nor is credit for any course taken at an unaccredited or foreign institution.
TIME LIMIT
Candidates have six (6) calendar years from the time of enrollment in The Graduate School to complete the degree. Students who change degree programs during this six-year period may be granted an extension after review and approval by The Graduate School. In any event, courses used toward a master's degree must have been taken within six calendar years of graduation.
DOCTOR OF PHILOSOPHY
Core courses are required for the program. A basic science and/or applied
science concentration must be selected at the first meeting of the student's
master's committee. For the basic science concentration, students must take at
least 4 credit hours in 500- or 600- level courses in basic mechanisms of
disease and at least 6 credit hours of 500- level biochemistry or cell biology.
See listings under the Biochemistry and Cellular and Molecular Biology program
for information on these courses. For the applied science concentration,
students must take at least 6 credit hours of 600- level epidemiology and at
least 5 credit hours of 500- or 600- level statistics. In addition, students
must complete a minimum of 8 hours of coursework in a specified discipline, 5 or
more hours of electives, and 6 hours of Thesis 500. Exceptions to accommodate
students with specific interests must be approved by the Joint Graduate
Coordinating Committee after application, in writing, to the director. Areas of
emphasis may include hematology, oncology,
comparative pathology, comparative pharmacology, toxicology, immunology, genetics,
infectious disease or biochemistry of disease. At least 24 hours of coursework,
including a minimum of 6 hours at the 600 level , and 24 hours of Dissertation
600 are required for a total of 48 hours.
Minimum Coursework : for Students with professional degrees, i.e., M.D., D.V.M., D.D.S.
Eighteen (18) hours of graduate coursework are required beyond the professional degree. At least six hours of 600-level courses must be included. In addition, at least twenty-four (24) hours of dissertation work in course number 600 are required [forty-two (42) hours total].
Minimum Coursework: for Master's graduates
Twenty-four (24) hours of graduate course-work are required beyond Master's. At least six hours of 600-level courses must be included. In addition, at least twenty-four (24) hours of dissertation work in course number 600 are required [forty-eight (48) hours total].
DOCTORAL COMMITTEE
Students must consult with the CEM program director on selection of a doctoral advisor (or temporary advisor) upon entry into the graduate program. During the first year of graduate study, the student shall select a doctoral advisor and, together with the latter, identify a doctoral committee composed of four faculty members, three of whom, including the chairperson (advisor), must be approved by the Graduate Council to direct doctoral research. At least one member must be from a department other than that of the student's major field, one member from the College of Veterinary Medicine, and one member from The UT Graduate School of Medicine. The director, after consulting with the Joint Graduate Coordinating Committee, must approve the Doctoral Committee to ensure that balance exists, and that the CEM program is appropriately represented. Exceptions to these requirements, to accommodate students with specific interests, must be approved by the Joint Graduate Coordinating Committee after application, in writing, to the director. The Doctoral Committee has primary responsibility, subject to Graduate Council policies, for the degree work of the student. The Doctoral Committee should plan, and must approve all coursework, certify the student's mastery of the subject matter of the field of study by a comprehensive examination, direct the research, and recommend the dissertation for approval and acceptance by The Graduate School. The Doctoral Committee should meet at least twice a year.
The student's responsibility is to coordinate the scheduling of the meetings of the Doctoral Committee and to obtain and/or prepare the materials required, such as appropriate Graduate School forms, transcripts, progress reports and research proposals for committee meetings. The student's progress will be monitored by the program director. It is incumbent upon students to promptly honor requests for progress reports.
Changes in membership of the Doctoral Committee MUST be done by submission to The Graduate School a completed Recommended Doctoral Committee Appointment Form, with signatures of the members removed and added to the committee. The signature of the director of the CEM Joint Graduate Coordinating Committee is also required. The Admission to Candidacy Form submitted by the student after completion of the comprehensive examination MUST have the signatures of members of the CURRENT Doctoral Committee.
DOCTORAL COMPREHENSIVE EXAMINATION
This examination should be taken when the student has completed, or nearly completed, all prescribed courses and must be completed at least two full semesters prior to the date the degree is to be conferred. Its successful completion indicates that, in the judgment of the faculty, the doctoral student can think analytically and creatively, has a comprehensive knowledge of the field and the specialty, knows how to use academic resources, and is deemed capable of completing the dissertation. The comprehensive examination must be passed prior to admission to candidacy. Candidate must adhere to the following guidelines:
1. The student shall declare, with approval of his/her Doctoral Committee and at the time of the student's first meeting with the Committee, a major study area and one to three minor areas. These shall be:
2. The examination shall be in two parts: a written examination followed by an oral examination. The written examination shall be a closed book examination conducted over one to three days. Questions given to the student on one day shall be completed on that day. The oral examination shall be held within three weeks after completion of the written examination. The oral examination at minimum shall cover the primary and secondary areas appropriately.
3. The Program Director shall appoint the Comprehensive Examination Coordinator for the examination process. The Program Director shall solicit nominations of at least three faculty members from the student's Advisor for consideration.
4. The Comprehensive Examination Coordinator and the Doctoral Committee shall be responsible for preparing and administering the examination. The Coordinator shall work with the Advisor and the rest of the Doctoral Committee to set the written examination. He/she shall ensure that questions reflect a concentration in the declared major and the minor areas are covered adequately. The written examination shall be administered and proctored by the Coordinator. The oral examination shall be administered by the Doctoral Committee under the direction of the Coordinator.
5. All CEM faculty members, including those not serving on the student's committee,
are entitled to submit questions appropriate to the student's educational background.
Questions from the student's previous instructors may also be given consideration.
6. The student shall pass the examination provided the Coordinator has established that:
7. All members of the Joint Graduate Coordinating Committee should be invited to attend the oral examination. They should be notified of the time and place.
8. Following the examination, a copy of the written examination, including corrections, will be maintained in the student's file in the Office of Research and Graduate Programs in the College of Veterinary Medicine.
9. The official results of the comprehensive examination must be reported to The Graduate School on the Admission to Candidacy application.
ADMISSION TO CANDIDACY
A student may be admitted to candidacy for the doctoral degree after passing the
comprehensive examination and maintaining at least a B average (minimum grade-point
average of 3.0) in all graduate coursework. Admission to candidacy must be applied
for, and approved, at least one full semester prior to the date the
degree is to be conferred. Each student is responsible for filing the Admission to
Candidacy, which must be signed by the Doctoral Committee and approved by The Graduate
School.
TRANSFER CREDITS
At the doctoral level, courses are not officially transferred although they may be used to meet degree requirements. If a requirement has been met through coursework in another program, the student may petition the Joint Graduate Coordinating Committee for a waiver of this requirement.
CONTINUOUS REGISTRATION
The student must register continuously for course number 600 (minimum of 3 hours per term) from the time the doctoral research proposal is approved, admission to candidacy is accepted, or registration of course number 600 is begun, whichever comes first. This includes summer semesters and the semester in which the dissertation is approved and accepted by The Graduate School. A minimum total of 24 hours of course number 600 is required before the dissertation will be accepted.
FINAL EXAMINATION (DEFENSE OF DISSERTATION)
A doctoral candidate must pass an oral defense of the dissertation. The dissertation, in the form approved by the major professor, MUST be distributed to the committee at least two weeks before the examination. The examination must be scheduled through the Graduate Admissions and Records Office at least one week prior to the examination and must be conducted in University facilities. Final examinations not properly scheduled must be repeated. The examination is announced publicly and is open to all faculty members. The defense of dissertation will be administered by ALL members of the doctoral committee after completion of the dissertation and all course requirements. This examination must be passed at least two weeks before the date of submission and acceptance of the dissertation by The Graduate School. Results of the defense must be submitted by the dissertation deadline.
The final examination should also fulfill the following CEM guidelines:
1. A draft of the thesis should be placed in the CEM Office of Graduate Programs one week prior to the final examination and be available to all interested persons at The University of Tennessee.
2. A seminar should be presented by the student. This seminar should be announced through the CEM Office of Graduate Programs and be open to all interested persons at The University of Tennessee.
3. Appropriate seminar announcements should identify this as a dissertation defense.
4. At the end of the presentation, questions shall be open to the audience and be appropriate to that presentation.
5. An oral defense of the dissertation, by the student, will be conducted by the Doctoral Committee immediately following the seminar. It is open to all faculty members.
DISSERTATION
The dissertation represents the culmination of an original research project completed by the student. The organization, method of presentation, and subject matter of the dissertation are important in conveying to others the results of such research. Funding for dissertation research will be identified by the student after consultation with the doctoral advisor. The student shall prepare, prior to initiation of the project, a proposal to include title, hypothesis, rationale, objectives, literature review, materials and methods, and budget. The student's Doctoral Committee and the Joint Graduate Coordinating Committee must approve the proposed research project in writing.
A student should be registered for the number of dissertation hours representing the fraction of effort devoted to this phase of the candidate's program. Thus, a student working full time on the dissertation should register for 12 hours of course number 600 per semester.
Two copies of the dissertation (prepared according to the regulations in the current edition of the UTK Guide to the Preparation of Theses and Dissertations) must be submitted to and accepted by The Graduate School. Each copy must include an approval sheet, signed by all members of the Doctoral Committee, which certifies to The Graduate School that they have examined the final copy and found that its form and content demonstrate scholarly excellence. Doctoral forms and a thesis card are also submitted at this time.
TIME LIMIT
Comprehensive examinations must be taken within five years, and all requirements must be completed within eight years from the time of a student's initial enrollment in the doctoral degree program.
ACADEMIC STATUS
GRADE-POINT AVERAGE
Graduate students must maintain a cumulative grade-point average (GPA) of at least a 3.0 in all graduate courses taken for a letter grade of A-F. Grades of S/NC, P/NP, and I, which have no numerical equivalent, are excluded from this computation. No student may repeat a course for the purpose of raising a grade already received, with the exception of NC. A graduate student may not do additional work or repeat an examination to raise a final grade.
TERMS OF PROBATION
If, upon completion of nine hours of graduate coursework, a student's GPA falls below 3.0, the student will be placed on academic probation. A student will be allowed to continue graduate study in subsequent semesters if each semester's GPA is 3.0 or greater. Upon achieving a cumulative GPA of 3.0, the student will be removed from probationary status.
DISMISSAL
If a student is on academic probation, the degree status will be terminated by The Graduate School if the student's semester GPA falls below a 3.0 in a subsequent semester. When the particular circumstances may be deemed to justify continuation, and upon recommendation by the CEM director and approval of The Graduate School, a student on probation whose semester GPA is below a 3.0 may be allowed to continue on a semester-by-semester basis.
Termination of a student from the program is accomplished by written notice to the student with a copy to The Graduate School. The Graduate School may evaluate the student's record to determine whether the student is eligible to apply for a change of status and register in another area of study.
Registration for courses in the CEM program by students dismissed from the program will
not be permitted, except by written authorization from the program director.
INCOMPLETE GRADES
"I" is a temporary grade indicating that the student has done satisfactorily in the course but, due to unforeseen circumstances, has been unable to complete all requirements.
All incompletes MUST be removed within one semester, excluding the summer semester. If a supplementary grade report has not been received in the Office of Graduate Admissions and Records at the end of the appropriate semester, the "I" will be changed to an "F." The course will not be counted in the cumulative grade-point average until a final grade is assigned.
No student may graduate with an "I" on his/her record.
METHOD/TIME FRAME FOR NOTIFICATION OF "CHANGE OF PROGRAM"
To change a major program of study, a student must complete a Request for Change of Graduate Program form. The form requires the signature of the director/head of the program in which admission was previously granted. Acceptance into a new program is contingent upon a review and recommendation by that program. Students not accepted into the program requested remain in the program in which he/she has been formerly admitted. Results of each request for program change are communicated to the student by mail by The Graduate School. Program changes must be accomplished within one semester of the request for change.
EXPECTATIONS FOR GOOD STANDING
Students in the CEM Program are expected to maintain a 3.0 cumulative grade-point average on all graduate courses graded A through F. For all other courses a grade of either P or S must be received. In addition, students are expected to make reasonable progress in their thesis research after projects have been approved. It is expected that they will complete thesis research projects within three years.
ACADEMIC HONESTY
EXPECTATIONS
Plagiarism or academic cheating of any description (during closed-book examinations, thesis preparation, manuscript preparation and research) is considered a serious breach in academic honesty, as is falsification of data.
VIOLATIONS
Violations of academic honesty by a student should be reported in writing to the Joint Graduate Coordinating Committee. The student will be notified, in writing, of the charge(s) by the Joint Graduate Coordinating Committee within seven days of the latter receiving the charge. This committee will investigate the circumstances of the alleged offense by meeting with both the accuser and the accused and either impose a penalty or dismiss the charges within 30 working days of student notification of the charge (unless an extension requested by the student is approved).
PENALTIES
Appropriate penalties for violation of academic honesty are probation, suspension or
dismissal. The exact penalty will depend on the circumstances under which the violation
was committed.
APPEAL
After a hearing by the Joint Graduate Coordinating Committee, a student dissatisfied with the decision rendered may appeal the decision to the Academic Review Board of The Graduate School in the manner detailed in "Hilltopics."
GRIEVANCES
All grievances of graduate students or members of the Graduate Faculty (other than academic honesty issues) must be made in writing to the Joint Graduate Coordinating Committee. If applicable, the subject of the charge must be notified, in writing, of the grievance within seven days of receiving the written allegation by the program director. The student or faculty member must present details of the grievance in person and provide documentation of the issue. The Joint Graduate Coordinating Committee shall attempt to render a decision to solve the problem within 30 working days of receiving the grievance, unless an extension requested by any of the parties involved is approved. If the student or Committee member is not satisfied by the decision of the Joint Graduate Coordinating Committee, further appeals may be made to the Dean of The Graduate School, the Graduate Council and the Chancellor. A copy of the Appeals Procedure is available in the Office of Graduate Admissions and Records.
ADMINISTRATION OF THE PROGRAM
The CEM Graduate Program is an intercollegiate program administered by The UTK Graduate School through the College of Veterinary Medicine. Admission and graduation requirements of The Graduate School will pertain. The program will be under the administration of a Joint Graduate Coordinating Committee. The Joint Graduate Coordinating Committee and its director are appointed by the Dean of the College of Veterinary Medicine in consultation with the Associate Vice Chancellor and Dean of The Graduate School and by the Dean of The UT Graduate School of Medicine. A minimum of four representatives and a maximum of six representatives will comprise the Joint Graduate Coordinating Committee. Equal representation from the College of Veterinary Medicine and The UT Graduate School of Medicine is required; however, other University faculty members who have been admitted to the program may also serve.
The Joint Graduate Coordinating Committee has the following charges:
1. Advise the program director on the composition of all student advisory committees for both doctoral and master's degrees. The director of the Joint Graduate Coordinating Committee nominates doctoral committees for approval by the Dean of The Graduate School.
2. Develop and coordinate the curriculum for the graduate program in consultation with the designated faculty of the program.
3. Recommend admission of applicants on advice of an Admissions Committee appointed by the Joint Graduate Coordinating Committee.
4. Appoint the Comprehensive Examination Committee monitor.
5. Ensure that appropriate guidelines are in place, approved, and implemented.
6. Be responsible for ensuring that the policies and regulations of The Graduate School are fulfilled by all participants in the program.
7. Be responsible for coordination of activities relevant to academic honesty and/or grievances.
8. Review and recommend approval of the program for each student on the admission to candidacy application.
9. Recommend the appointment of faculty members to the program.
Several departments participating in the Comparative and Experimental Medicine Graduate Program offer courses approved by the program and by The Graduate School. Faculty participating in the CEM program are also approved by the program. (Code for course offerings is: E = offered every semester; F = offered in the fall; Sp = offered in the spring; and A = alternate year)
Students not enrolled in a graduate program must obtain approval from the Joint Graduate Coordinating Committee prior to registration in Special and Advanced Topic courses of the CEM program.
COLLEGE OF VETERINARY MEDICINE
Participating departments include: Animal Science, Comparative Medicine, Microbiology,
Pathology, Large Animal Clinical Sciences and Small Animal Clinical Sciences. Several
faculty in the Department of Microbiology hold joint appointments in the College of
Veterinary Medicine. Therefore, please check the current Graduate Catalog and semester
timetable for listing of microbiology courses and times.
500 THESIS (1-15). P/NP only. E
501 SPECIAL TOPICS IN COMPARATIVE AND EXPERIMENTAL MEDICINE
(1-6). Specialized experience in comparative and experimental medicine.
Prerequisite: Consent of instructor. May be repeated. Maximum 6 hrs. E
502 REGISTRATION FOR USE OF FACILITIES
(3-15). Required for the graduate student who is not otherwise registered during
any semester when such a student uses University facilities and/or faculty time before
degree is completed. May not be used toward degree requirements. May be repeated. S/NC
only.E.
503 PREDICTIVE TOXICOLOGY (3). Principles and techniques of predictive toxicity: structure-activity relationships, expert systems, neuralnets and molecular similarity. Sp, A
505 LABORATORY ANIMAL CARE AND USE (2).
Review of basic laboratory animal care and use as prerequisite to conducting research
using animal subjects. Compliance issues and techniques. F
506 EXPERIMENTAL ANIMAL SURGERY (3). Competence in
performing humane surgical modification to experimental animals. Techniques of anesthesia,
drug administration, and postoperative care. Prerequisite: Embryology, parasitology,
physiology and/or consent of instructor. 1 hr. and 2 labs. F
530 WILDLIFE DISEASES (2). Necropsy of birds and
mammals. Recognition of various diseases and methods of preparing pathological materials
in field and lab. Investigative procedures concerning wildlife diseases. Prerequisite: 1
yr. biology, Wildlife and Fisheries Science 444 or 445, or consent of instructor. (Same as
Forestry, Wildlife & Fisheries Science 530) F, A
551 MAMMALIAN ORGANOLOGY (3). Microscopic study of structure of organs and major organ systems. Prerequisite: Embryology, histology and/or consent of instructor. (Same as An Sci 551) 2 hrs. and 1 lab. F
552 ANATOMY OF DOMESTIC CARNIVORES (4). Gross dissection by systems and regions of the dog with comparison to cat and lecture/demonstration. Prerequisite: Consent of instructor. (Same as An Sci 552) 1 hr. and 3 labs. F
561 PHARMACOLOGY (4). Principles of pharmacokinetic
and pharmacodynamic properties of drugs including mode of action, pharmacologic effects,
chemical and physical properties, metabolism, toxicities, important idiosyncrasies, and
clinical applications. Prerequisite: Consent of instructor. F
600 DISSERTATION (3-15). P/NP only. E
602 SURGICAL PATHOLOGY (1-2). Examination of biopsy specimens and interpretation of observations. Preparation of specimens for sectioning. Prerequisite: Consent of instructor. May be repeated. Maximum 3 hrs. E
603 CORRELATIVE PATHOLOGY (1-3). Gross and microscopic postmortem examination of animals. Correlative interpretation of clinical diseases and lesions. Prerequisite: Consent of instructor. May be repeated. Maximum 6 hrs. E
604 VETERINARY PATHOLOGY SEMINAR (1). Microscopic slides and transparencies of lesions from cases examined by pathologists, residents, and graduate students. Interpretation of observations. Prerequisite: Consent of Instructor. May be repeated. Maximum 4 hrs. E
605 PATHOBIOLOGY SEMINAR (1). Subjects of current interest in biomedical science. Students present one seminar per term enrolled. Prerequisite: Consent of instructor. May be repeated. Maximum 4 hrs. Class meets once monthly. E
606 CLINICAL EPIDEMIOLOGY (3). Theory and principles of design
implementation and analysis of clinical research. Laboratories include appraisal
of biomedical literature and design of a proposal for a clinical research project.
Prerequisite: Consent of instructor. Sp
607 DIAGNOSIS AND PATHOGENESIS OF VIRUS DISEASES OF DOMESTIC ANIMALS (3). Advanced study of virus diseases important to domestic animals: virus biology, pathogenesis, pathology and diagnosis, technical training in virus diseases diagnosis. Prerequisite: Consent of instructor. 2 hrs. and 1 lab. Sp
608 DESCRIPTIVE AND APPLIED EPIDEMIOLOGY (3). Principles of epidemiology and their historic and modern application to diseases of animals. Host-agent relationships, measurement of disease frequency, animal production and disease monitoring and control, field investigations and animal health economics. Prerequisite: Consent of instructor. F
609 MECHANISMS OF DISEASE (4). Advanced topics in
pathology and mechanisms of disease: patho-physiology, cellular degeneration,
inflammation, immunopathology, hemostasis. Principal biochemical and morphologic responses
of various cells, tissues, and organs to injury and other metabolic derangements. Selected
contemporary topics from current literature and textbooks. Prerequisite: Consent of
instructor. Sp, A
610 ADVANCED TOPICS IN COMPARATIVE AND EXPERIMENTAL MEDICINE
(1-3). Specialized in-depth experience in the various disciplines, current and
future research methodology, recent advances in instrumentation in analytical techniques
for comparative medicine. Prerequisite: Consent of instructor. May be repeated. Maximum 12
hrs. E
651 ADVANCED TOPICS IN ANIMAL ANATOMY (1-4).
Current and future research methodology, laboratory situations, recent advances in
quantitative techniques for gross and microscopic anatomy. Prerequisite: Consent of
instructor. May be repeated. (Same as An Sci 651) Maximum 6 hrs. E
652 DISORDERS OF THE ENDOCRINE SYSTEM
(2). Pathological and physiological aspects of diseases involving endocrine
glands of various animal species. Prerequisite: Animal Science 521 (Animal Physiology)
or consent of instructor. (Same as An Sci 652) Sp, A
UT GRADUATE SCHOOL OF MEDICINE
Participating departments include: Anesthesia, Medicine, Medical Biology, Obstetrics
and Gynecology, Pathology, Pediatrics, Radiology, and Surgery.
500 THESIS (1-5). P/NP only. E
502 REGISTRATION FOR USE OF FACILITIES
(3-15). Required for the student not otherwise registered during any semester
when student uses University facilities and/or faculty time before degree is completed.
May not be used toward degree requirements. May be repeated. S/NC only. E
508 GRADUATE RESEARCH PARTICIPATION (3).
Advanced research techniques studied while conducting individual biomedical
research projects under supervision of faculty. Prerequisite: Consent of instructor.
Open to all graduate students. May be repeated with consent. Maximum 9 hrs.
S/NC only. E
521 PRINCIPLES OF ONCOLOGY (3). Lectures, classroom
discussion, and case reports surveying the major topics of oncology. Prerequisite: Biology
220-230 or consent of instructor.
541 MOLECULAR BASIS FOR METABOLIC DISEASE (4). Metabolic disorders of humans and animals. Emphasis on molecular mechanisms in inborn errors of metabolism, toxic reactions, and deficiency states. Clinical and pathologic correlations. Prerequisite: BCMB 410-419 or equivalent. F, A
545 CLINICAL GENETICS (3). Human genetic disorders: new developments in cytogenetics, molecular genetics, clinical diagnoses and prevention. Prerequisite: Biology and genetics background or consent of instructor.
600 DOCTORAL RESEARCH AND DISSERTATION (3-15). P/NP only. E
610 MEDICAL BIOLOGY SEMINAR (1). Invited speakers. Topics posted in advance. May be repeated. S/NC only. F, Sp
611 ADVANCED TOPICS IN MEDICAL SCIENCE (1-3). New developments in biological research applicable to clinical medicine. Primarily for doctoral candidates in Comparative and Experimental Medicine. Prerequisite: Consent of instructor. May be repeated. Maximum 6 hrs. F, Sp
652 SPECIAL TOPICS IN PATHOLOGY (1-3). Pathologic anatomy, biochemical pathology and related areas. Primarily for doctoral candidates in Comparative and Experimental Medicine. Prerequisite: Consent of instructor. May be repeated. Maximum 6 hrs. F, Sp
FINANCIAL SUPPORT
The Graduate School administers the Hilton A. Smith Graduate Fellowships, the Herman E.
Spivey Graduate Fellowships and the National Alumni Association Graduate Fellowships.
These awards are for full-time study at UT Knoxville, and awardees are selected on the
basis of high achievement, broad intellectual ability, and potential for significant
career contributions.
Whereas the Comparative and Experimental Medicine Program does not offer specific graduate fellowships or assistantships, fellowship awards often may be arranged with individual investigators. The College of Veterinary Medicine does offer post-graduate fellowships when funds are available. Information on these are as follows:
1. FIVE (5) POSTGRADUATE FELLOWSHIPS:
Awarded (as funds are available) for a three-year period. Applications are reviewed several times per year. Persons with a professional degree in the health sciences (D.V.M., M.D., D.D.S.) who wish to pursue a Ph.D. program are given priority.
NOTIFICATION OF AWARD:
Awardees are notified by a letter from the Director of Research and Graduate Program, College of Veterinary Medicine
ADDRESS REQUESTS TO:
Office of Research and Graduate Programs
Department of Comparative Medicine
College of Veterinary Medicine
The University of Tennessee
P. O. Box 1071
Knoxville, TN 37901-1071
2. FIVE (5) ANATOMIC PATHOLOGY RESIDENCY-GRADUATE STUDIES FELLOWSHIPS:
One awarded yearly (as funds are available) for a five-year period. Applications are reviewed annually by the Departmental Graduate Studies Committee. Top candidates will be invited for an interview by members of the Pathology Department.
SELECTION CRITERIA/PRIORITIES:
The only requirement is a veterinary degree. However, applicants with practice experience are preferred. In addition, pertinent laboratory and/or graduate experience will be considered in the selection of candidates.
NOTIFICATION OF AWARD:
Candidates will be notified about the outcome of their application for Pathology Fellowships by letter from the Pathology Graduate Studies Committee.
ADDRESS REQUESTS TO:
Dr. David O. Slauson
Department of Pathology
College of Veterinary Medicine
The University of Tennessee
P. O. Box 1071
Knoxville, TN 37901-1071
3. NIH POSTDOCTORAL FELLOWSHIPS IN MOLECULAR PATHOBIOLOGY
The Department of Pathology provides fellowships in research training leading to the Ph.D. degree for veterinarians who already have had at least two years of residency training in pathology. The program is funded by the National Institutes of Environmental Health Sciences and is aimed at producing individuals who, by virtue of their training, will be uniquely equipped to address such important NIEHS research priorities as the molecular and genetic basis for environmental diseases, genetic and membrane events that may control differentiation and development, mechanisms of receptor-mediated pathobiology including transmembrane signal transduction, molecular mechanisms of chemical carcinogenesis, and the genetic and molecular basis for immunologic susceptibility, inflammatory reactivity, and predisposition.
SELECTION CRITERIA/PRIORITIES:
Those with the strongest academic records and who appear to offer the greatest career potential will be given selection preference. Candidates should hold the D.V.M. degree (or equivalent), have at least two years of residency training in pathology, and present strong academic credentials with evidence of interest and commitment to graduate work and research.
ADDRESS REQUESTS TO:
Dr. David O. Slauson
Department of Pathology
College of Veterinary Medicine
The University of Tennessee
P.O. Box 1071
Knoxville, TN 37901-1071
4. FIVE (5) GRADUATE SCHOOL OF MEDICINE GRADUATE RESEARCH ASSISTANTSHIPS
Awarded (as funds are available) for a two to four year period. Applications are reviewed several times per year. Persons with a professional degree in the health sciences (M.D., D.V.M., D.D.S., D.M.D.) who wish to pursue a Ph.D. program are given priority. Fee waivers only are available.
NOTIFICATION OF AWARD:
Awardees are notified by a letter from the Dean of the Graduate School of Medicine.
ADDRESS REQUESTS TO:
Office of the Dean
Attn: Graduate Research Assistantship Program
Graduate School of Medicine, Box 94
The University of Tennessee Medical Center
1924 Alcoa Highway
Knoxville, TN 37920
APPENDIX
CORE COURSES REQUIRED BY THE COMPARATIVE AND EXPERIMENTAL
MEDICINE GRADUATE PROGRAM
A. Biochemistry, Cellular, and Molecular Biology
BCMB 512 (Advanced Molecular Biology) --3 credits.
and
BCMB 513 (Advanced Protein Biochemistry and Cell Biology II) --3 credits.
B. Disease Mechanisms
Medical Biology 541 (Molecular Basis for Metabolic Disease)--4 credits.
or
Comparative and Experimental Medicine 609 (Mechanisms of Disease) --4 credits.
or go to